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Documents requested prior to an Inspection

Information is typically requested before the inspection, including:

  • An up to date version of the Pharmacovigilance System Master File (PSMF).

  • Organisation charts/lists of key personnel involved in pharmacovigilance activities.

  • Written procedures and processes relating to the pharmacovigilance system.

  • Line listings of adverse events.

  • List of any organised data collection systems.

  • Periodic Safety Update Reports (PSURs) and Risk Management Plans (RMPs).

  • Lists of safety signals identified by the MAH and associated key dates of processing.

  • Lists of safety variations submitted/due for submission by the MAH.

  • Current copies of approved reference safety information (e.g. Summary of Product Characteristics (SmPCs) and Patient Information Leaflets (PILs)).